Heilongjiang Zhenbaodao Pharmaceutical, Tianjin Hongri Pharmaceutical, Anguo Juyaotang Pharmaceutical, Anhui Jiuzhou Fangyuan Pharmaceutical

In order to meet the needs of modern TCM clinical and disciplinary changes, traditional decoction pieces can no longer meet and adapt to people's needs, and the use of advanced technology, scientific extraction, low-temperature concentration, spray drying and other processes made of Chinese medicine formula particles have been used as a new type of Chinese medicine, because it does not need to fry, attract fast, stable curative effect is more and more accepted by people. Chinese medicine formula granule products are the basis to further inherit and carry forward the advantages and characteristics of traditional Chinese medicine, make full use of modern science and technology methods and means, through the application of high-tech, new ways to serve the clinical practice of traditional Chinese medicine, its development is in line with modern life, Chinese medicine formula granule industry is the future to replace Chinese medicine pieces of fine molecular industry, maintain an annual growth of 40%~50%, There is great room for future development.

Chinese medicine formula granules are granules made by extracting and concentrating single Chinese medicine decoction pieces for clinical use in traditional Chinese medicine formulas. Previously known as single herb concentrated granules in China, the trade names and folk names also include decocted traditional Chinese medicine decoction pieces, new decoction pieces, refined decoction pieces, beverage type decoction pieces, scientific traditional Chinese medicine, etc. It is a new formula medication made from traditional Chinese medicine decoction pieces through extraction, separation, concentration, drying, granulation, packaging and other production processes, with unified specifications, dosage and quality standards. Conceptually speaking, the so-called single ingredient Chinese medicine formula granules are a series of pure Chinese medicine products made from traditional Chinese medicine decoction pieces that meet processing standards as raw materials, extracted, concentrated, separated, dried, granulated, and packaged through modern pharmaceutical technology. It ensures all the characteristics of the original traditional Chinese medicine decoction pieces, which can meet the needs of physicians for dialectical treatment, with adjustments according to the symptoms. It has strong medicinal properties, high efficacy, and many advantages such as no need for decoction, direct ingestion, small dosage, rapid action, complete ingredients, precise therapeutic effect, safety and hygiene, convenient carrying and storage, easy preparation, and suitability for industrial production. In recent years, traditional Chinese medicine formula granules have developed rapidly in countries and regions such as the United States, Europe, Australia, South Korea, Japan, Taiwan, and Hong Kong. South Korea, Japan, Taiwan, and Hong Kong not only meet the needs of their respective regions but also export in large quantities. The modernization of Chinese medicine in China is seriously lagging behind, and the promotion of Chinese medicine formula granules is extremely slow. Its effective ingredients, nature and taste, meridian tropism, indications, and efficacy are completely consistent with those of traditional Chinese medicine decoction pieces, maintaining all the characteristics of traditional Chinese medicine decoction pieces, which can not only ensure the characteristics of traditional Chinese medicine, such as monarch, minister, assistant, envoy, dialectical treatment, flexible addition and subtraction, superior to traditional Chinese patent medicines and simple preparations, but also eliminate the trouble of patients' traditional decoction. At the same time, it can also flexibly take single flavor granules, which is hygienic and effective.

One, Convenient

1. It can replace traditional decoction pieces for TCM doctors to treat clinical syndrome differentiation;

2, do not need to cook, when used, warm water is mixed into powder;

3, small dose fine packaging, infusion concentration can be adjusted by itself, small dose;

4, unit drug light weight, small size, convenient storage and transportation;

5, composite aluminum foil packaging, easy to carry and save;

6, safety and health, moisture-proof and mothproof, long shelf life;

7, the drug name printing is clear, the formula is clean and hygienic, which is conducive to strengthening the management of traditional Chinese medicine.

Two, Security

1, raw materials are processed traditional Chinese medicine slices with strict quality control;

2. Extracted, separated, concentrated, dried, granulated and packaged by modern pharmaceutical technology;

3. Uniform specifications, consistent standards, accurate and stable curative effect.

Three, Effective

1, and traditional decoction pieces have the same effective ingredients, sex and taste, treating effect;

2, the unit mass of the effective ingredient is several times higher than the traditional decoction pieces;

3, strong, high efficacy, rapid effect.

For, How to take

Pour each bag of medicine in a dose (daily dose) into the same cup, soak in a small amount of warm water for 1-2 minutes, then rinse with appropriate amount of boiling water, stir, mix and seal for 2-3 minutes until fully dissolved, take it in 2 times, according to the efficacy of the prescription, according to the doctor's advice to choose before or after meals.

(1) The air intake device is equipped with a sub-high efficiency filter, so that the air intake reaches 100,000 level purification. Air filters, dehumidifiers, heaters, etc. are made of modular, easy to disassemble, maintain, maintain, and fresh air is dehumidified;

(2) The tower wall is equipped with a cold air jacket device, which solves the problem of Chinese medicine extract sticking to the wall, and the wall temperature is low, which will not cause the material to coking metamorphism;

(3) The atomizer is designed specifically for the characteristics of the extract, while increasing the distance between the atomization plate and the top of the drying tower to avoid the roof of the material;

(4) The equipment is provided with a gas sweep device in the cone part, thus accelerating the flow of the material on the cone;

(5) Automatic control of inlet air temperature to ensure that the color, aroma and taste of the material will not be destroyed;

(6) Two-stage cyclone dust removal device is used for material collection;

(7) CIP cleaning system, equipment cleaning is convenient, in line with GMP requirements;

(8) The control system adopts PLC program control, and the entire operating system is simple and easy to understand, making it more convenient for workers to operate.

For the Chinese medicine drying process, the company has optimized and improved some production equipment after years of production practice, and independently developed a special dryer for Chinese medicine formula particles. The equipment is a drying device which uses a high-speed centrifugal atomizer to disperse the material into a mist, fully contact with the hot air to complete the instant drying, and form powder or granular finished products.

(1) The air intake device is equipped with a sub-high efficiency filter, so that the air intake reaches 100,000 level purification. Air filters, dehumidifiers, heaters, etc. are made of modular, easy to disassemble, maintain, maintain, and fresh air is dehumidified;

(2) The tower wall is equipped with a cold air jacket device, which solves the problem of Chinese medicine extract sticking to the wall, and the wall temperature is low, which will not cause the material to coking deterioration;

(3) The atomizer is designed specifically for the characteristics of the extract, while increasing the distance between the atomization plate and the top of the drying tower to avoid the roof of the material;

(4) The equipment is provided with a gas sweep device in the cone part, thus accelerating the flow of the material on the cone;

(5) Automatic control of inlet air temperature to ensure that the color, aroma and taste of the material will not be destroyed;

(6) Two-stage cyclone dust removal device is used for material collection;

(7) CIP cleaning system, equipment cleaning is convenient, in line with GMP requirements;

(8) The control system adopts PLC program control, and the entire operating system is simple and easy to understand, making it more convenient for workers to operate.